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Home Articles Dental News Get a Filling or Print A New Smile?
Get a Filling or Print A New Smile?

Sting. Painful teeth. One in 10 people suffers from tooth sensitivity caused by enamel abrasion. However, new dental supplies technology does not provide a short-term solution like providing special toothpastes or fillings. Instead, it can print a new layer of enamel onto the teeth - even stimulating the body to develop new teeth.
Dr Antonios Anastasiou hopes to print new teeth for you. He is not yet in place, but the collaboration of materials scientists, laser engineers and clinicians at the University of Leeds in the UK has reached an important milestone. They can print a new layer of enamel on the surface of the teeth, preventing the exposure of tiny holes called dentinal tubules, which can cause a sense of chilling and cooling, and become a breeding ground for bacteria that cause tooth decay.
At present, the materials used by dentists to repair enamel cannot provide more temporary repairs. They will disappear over time and leave gaps that bacteria can obtain.
The technology that Dr. Anastasiou is exploring should overcome these problems.
"We use materials similar to natural minerals such as hydroxyapatite or other types of calcium phosphate," explains Dr. Anastasiou.
A femtosecond laser can be used to print new material onto the tooth, which heats the small iron oxide nanoparticles in the material to adhere it to the existing tooth surface. The small heating area avoids damage to the surrounding teeth. They can also add germanium and other exotic elements to provide new material antibacterial properties.
"What we are doing is figuring out how to prevent bacteria from accumulating on the surface." - Dr. Antonios Anastasiou, University of Leeds, UK
"We can not only restore enamel with materials similar to the original minerals of the teeth, we can also improve it. What we are doing is figuring out how to prevent bacteria from colonizing the surface," said Dr. Anastasiou.
His solution is also more lasting. Although the current repair material such as resin will shrink with time or temperature, his material does not. It is also a material that allows the gums to be easily reattached, helping to prevent gum infection around the mouth called periodontitis.
Currently, the technology is being tested as a dental school device to ensure that there are no long-term side effects and that it can adapt to the rigors of everyday life.
"Some patients have it in their mouths, are taking care of it, brushing their teeth, and during the eating process. If these tests are positive, then we can continue with clinical studies," he said.
Sensitivity
In the end, printed tinctures can be sold on the market in about five years, and can help those who suffer from enamel wear to enjoy hot and cold drinks without sensitivity.
"One of our professors said that he participated in this study because he wanted to drink his whiskey with ice,"
Dr. Anastati joked.
Printing a tooth restoration is one thing, but what if your body is stimulated to regenerate a lost or damaged tooth?
This is the goal of Dr. Igor Adameyko of the Medical University of Vienna, Austria, who tried to uncover how to use stem cells to induce the secret of new tooth formation.
But to do this, he first needs a map.
"For a long time, no one knew how many cell types and subtypes live in the teeth. This knowledge is crucial for understanding how this organ develops, grows, and maintains itself," said Dr. Adamae.
In order to carry out such a cell survey, he used a process called single cell transcriptomics. This new method can decompose cells one by one, measure RNA in thousands of cells at the same time -- a key molecule similar to DNA, which can control which gene instructions are implemented.
By examining the cell's RNA blueprint, researchers can figure out what its type and function are. Through this arduous process, the team has established an atlas of all cell types living in the teeth, which also helps him understand how different types of cells interact.
'Cells exchange signals. These signals are not some kind of ethereal signal, but they are very important. Molecules are made and secreted, and some cells have receptors that can bind these molecules. We can actually see these pairs in the dataset and predict these interactions, "he said.
Glial cells
With this knowledge, his team honed the ability to control the life and death of teeth, and to control the transformation of cells called glial cells (a cell that surrounds and isolates neurons) into dental stem cells that grow teeth.
Teeth come from two different types of embryonic tissue - epithelial cells produce enamel, and mesenchyme can turn into bone or a living tissue in the tooth called a dental pulp.
Dr. Adamiko and his team have also been studying the tooth development and regeneration in mice because they feed on hard food, so the mice's teeth are growing all their lives. Using special chemical manipulations, they made the rat's teeth transparent and observed what was happening to the glial cells.
This knowledge can help the dental equipment team find out how to activate glial cells to transform into new human stem cells, to grow new roots for regenerating active teeth, or to implant new nerves for dental implants.
"If this is present in human teeth, by doing so, we will be able to find some molecules that will strengthen the restoration of teeth," Dr. Adamiko said.